Cobal-based hydrogenation catalyst with TiO2/Al2O3 as the carrier and Co-Mo as the active component has good low-temperature activity, large specific surface area, large pore volume, uniform distribution of active elements, high hydrogenation activity, and good stability . It has a high conversion ability to complex organic sulfides. It is used for hydrodesulfurizing naphtha, residual oil, reforming, cracking gasoline, and other distillates.